2-Chlorobenzoic Acid → Methyl 2-chlorobenzoate
Reaktionsgleichung
[N+](=[CH2:3])=[N-].[Cl:4][C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]>CCOCC>[Cl:4][C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7]([O:9][CH3:3])=[O:8]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
An excess solution of diazomethane in ether was added to an ice-cooled and stirred solution of o-chlorobenzoic acid (7.6 g, 48.6 mmol) in 50 ml of ether. After concentration, the residue was distilled under reduced pressure to give a colorless transparent oil of methyl o-chlorobenzoate (6.0 g, 35.2 mmol, yield 72.4%, b.p. 92°-93° C./7 mmHg), which was assigned the structure by the following data:
Aufarbeitung
- temperaturecooled
- concentrationAfter concentration
- distillationthe residue was distilled under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-3266c0d51b2249708da94ad3e0457107
- Quelldatensatz
- uspto-grants-1988_10
- Patentnummer
- US04775692
Notizen zur Reaktion
Wird geladen…