1-Butanol → Butyl pyruvate

HRID 868772

Reaktionsgleichung

Reaktionsgleichung von HRID 868772
[C:1]([OH:6])(=[O:5])[C:2]([CH3:4])=[O:3].[CH2:7](O)[CH2:8][CH2:9][CH3:10]>O.C1(C)C=CC(S(O)(=O)=O)=CC=1.C1(C)C=CC=CC=1>[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH3:10])(=[O:5])[C:2]([CH3:4])=[O:3]

Komponenten

5

Edukt 2

HCID 2631-ButanolHCID 1060Pyruvic Acid

Produkt 1

HCID 523883Butyl pyruvateAusbeute 70,1 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 521998p-Toluenesulfonic acid monohydrateKatalysatorHCID 1140TolueneLösungsmittel

Reaktionsbedingungen

Temperatur
25 °C

Versuchsvorschrift

First, a toluene (1 L) solution of pyruvic acid (440 g, 5.0 mol), n-butanol (371 g, 5.0 mol) and p-toluenesulfonic acid monohydrate (2.5 g) was heated and refluxed for 16 hours while removing water under a nitrogen gas stream, whereby a first reaction solution was obtained. Next, the first reaction solution was cooled to room temperature (25° C.). Thereafter, toluene was removed under reduced pressure (40 mmHg) using an evaporator, and the residue was purified by reduced pressure distillation (40 mmHg, 93 to 100° C.), whereby butyl pyruvate (505 g, yield 70%) was obtained.

Aufarbeitung

  1. temperaturerefluxed for 16 hours
  2. customwhile removing water under a nitrogen gas stream, whereby a first reaction solution
  3. customwas obtained
  4. customThereafter, toluene was removed under reduced pressure (40 mmHg)
  5. customan evaporator
  6. distillationthe residue was purified by reduced pressure distillation (40 mmHg, 93 to 100° C.)

Quellen und Nachweise

ORD-Eintrag
ord-e3f4b785506842d7aa2cf4bb89d386b6
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08968975B2

Verknüpfte Notizen

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