Diisopropylethylamine → tert-Butyl 3-{3-[(4,4,4-trifluoro-2-{4-[(4-fluoro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-3-methylbutanoyl)amino]phenyl}propanoate

Reaktionsgleichung

[NH2:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[CH:5]=[CH:6][CH:7]=1.[F:17][C:18]([F:44])([F:43])[CH:19]([CH3:42])[CH:20]([C:24]1[CH:29]=[CH:28][C:27]([CH2:30][N:31]2[CH2:39][C:38]3[C:33](=[CH:34][CH:35]=[CH:36][C:37]=3[F:40])[C:32]2=[O:41])=[CH:26][CH:25]=1)[C:21](O)=[O:22].O.ON1C2C=CC=CC=2N=N1.CCN(C(C)C)C(C)C.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F>CN(C=O)C.O>[F:44][C:18]([F:17])([F:43])[CH:19]([CH3:42])[CH:20]([C:24]1[CH:25]=[CH:26][C:27]([CH2:30][N:31]2[CH2:39][C:38]3[C:33](=[CH:34][CH:35]=[CH:36][C:37]=3[F:40])[C:32]2=[O:41])=[CH:28][CH:29]=1)[C:21]([NH:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[CH:5]=[CH:6][CH:7]=1)=[O:22]