[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[O:11])=[CH:4][C:3]=1[O:19][CH3:20].O>O1CCCC1.[Pd]>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[O:11])=[CH:4][C:3]=1[O:19][CH3:20]3-(4-Hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propene-1-one (10 g) is dissolved in 100 g tetrahydrofuran, 0.2 g of Pd on activated carbon (Pd content: about 5% by weight, water content approx. 50% by weight, based on the total mass of the catalyst) is added and a hydrogenation is carried out at normal pressure and room temperature (approx. 20° C.). After removal of the catalyst and the solvent, 9 g of 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-propane-1-one is obtained. Yield: 89% of the theory.
Wird geladen…
