Water → HCID 18793861, Verbindung

HRID 893937Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 893937
[CH2:1]([O:3][C:4](=[O:11])[CH2:5][C:6]1[N:7]=[CH:8][S:9][CH:10]=1)[CH3:2].[OH2:12]>ClCCCl>[CH2:1]([O:3][C:4](=[O:11])[C:5]([C:6]1[N:7]=[CH:8][S:9][CH:10]=1)=[O:12])[CH3:2]

Komponenten

4

Edukt 2

HCID 962WaterHCID 4737345Ethyl 2-(1,3-thiazol-4-yl)acetate

Produkt 1

HCID 18793861HCID 18793861, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 111,2-DichloroethaneLösungsmittel

Versuchsvorschrift

Alternatively, the 1,3-thiazol-4-yl-glyoxyl ester is obtained by heating 17.1 g of 1,3-thiazol-4-yl-acetic acid ethyl ester in 50 ml of 1,2-dichloroethane together with 10.5 g of SeO2 with reflux on a water separator. When the separation of water is complete, the mixture is filtered with suction, the residue is washed with 1,2-dichloroethane, the combined dichloroethane phases are concentrated and the residue is distilled.

Aufarbeitung

  1. customWhen the separation of water
  2. filtrationthe mixture is filtered with suction
  3. washthe residue is washed with 1,2-dichloroethane
  4. concentrationthe combined dichloroethane phases are concentrated
  5. distillationthe residue is distilled

Quellen und Nachweise

ORD-Eintrag
ord-b9582bed11d04d15ab86b729fd7e044e
Quelldatensatz
uspto-grants-1981_08
Patentnummer
US04282220

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