Ethanol → (2,4-Dimethylthiophen-3-yl)methanol

HRID 904472Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 904472
[BH4-].[Na+].[CH3:3][C:4]1[S:5][CH:6]=[C:7]([CH3:11])[C:8]=1[CH:9]=[O:10].C(O)C>O>[CH3:3][C:4]1[S:5][CH:6]=[C:7]([CH3:11])[C:8]=1[CH2:9][OH:10]

Komponenten

5

Edukt 3

HCID 702EthanolHCID 4311764Sodium borohydrideHCID 111477702,4-Dimethylthiophene-3-carbaldehyde

Produkt 1

HCID 12875266(2,4-Dimethylthiophen-3-yl)methanol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

0.68 G. (18 mmol) of sodium borohydride was added in three portions to a solution of 10.08 g. (72 mmol) of 2,4-dimethylthiophene-3-carboxaldehyde in 120 ml. of ethanol. After 15 min., the reaction mixture was poured into water, extracted with ether, dried and the solvent evaporated. The resulting residue was recrystallized from hexane to yield 2,4-dimethyl-3-hydroxymethylthiophene, m.p. 80°-81° C.

Aufarbeitung

  1. extractionextracted with ether
  2. customdried
  3. customthe solvent evaporated
  4. customThe resulting residue was recrystallized from hexane

Quellen und Nachweise

ORD-Eintrag
ord-b7d87ca55c9d4cf4a21bc8b6ee985286
Quelldatensatz
uspto-grants-1980_10
Patentnummer
US04230872

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