Acetic Acid → tert-Butyl-(2R)-4-((6-(5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-1-oxo-1,2-dihydroisoquinolin-4-yl)methyl)-2-(hydroxymethyl)piperazine-1-carboxylate

Reaktionsgleichung

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([CH2:14][C:15]2[C:24]3[C:19](=[CH:20][CH:21]=[C:22](Br)[CH:23]=3)[C:18](=[O:26])[N:17](S(C3C=CC=CC=3)(=O)=O)[CH:16]=2)[CH2:10][C@@H:9]1[CH2:36][OH:37])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH:38]1([NH:41][C:42](=[O:60])[C:43]2[CH:48]=[C:47](B3OC(C)(C)C(C)(C)O3)[C:46]([CH3:58])=[C:45]([F:59])[CH:44]=2)[CH2:40][CH2:39]1.C(=O)([O-])[O-].[K+].[K+].C(O)(=O)C>CN(C=O)C.O>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([CH2:14][C:15]2[C:24]3[C:19](=[CH:20][CH:21]=[C:22]([C:47]4[CH:48]=[C:43]([C:42](=[O:60])[NH:41][CH:38]5[CH2:39][CH2:40]5)[CH:44]=[C:45]([F:59])[C:46]=4[CH3:58])[CH:23]=3)[C:18](=[O:26])[NH:17][CH:16]=2)[CH2:10][C@@H:9]1[CH2:36][OH:37])=[O:7])([CH3:3])([CH3:4])[CH3:2]