Sodium Hydroxide → diammonium fumarate

Following the examples of U.S. Pat. No. 4,839,461, a slurry of 11.6 g (0.1 mole) fumaric acid was dissolved in 30 ml water was mixed with 13 g of 30% aqueous solution of ammonium hydroxide (0.11 mol NH3). Carefully warming the slurry to boiling gave a clear solution. This solution was boiled to dryness over a period of 15 minutes to give a white crystalline solid. The solid was tumbled under nitrogen at 100 Torr, at 145°-150° C. for 8 hours to give an off-white glasslike solid weighing 13.2 g. This solid was dissolved in 40 g of an aqueous solution containing 4.0 g of sodium hydroxide to form a pale yellow solution, pH 8.5, containing 25% solids.

1. temperatureCarefully warming the slurry
2. customto boiling gave a clear solution
3. customto give a white crystalline solid
4. waitThe solid was tumbled under nitrogen at 100 Torr, at 145°-150° C. for 8 hours
5. customto give an off-white glasslike solid
6. customto form a pale yellow solution, pH 8.5

ORD-Eintrag

ord-21583dd0d823486f8b5e85af03899f77

Quelldatensatz

uspto-grants-1998_06

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US05773565