HCID 10910823, Verbindung → Spermine

HRID 968183

Reaktionsgleichung

Reaktionsgleichung von HRID 968183
C([CH:8]([CH2:24][CH2:25][NH:26][CH2:27][CH2:28][CH2:29][CH2:30][NH:31][CH2:32][CH2:33][CH2:34][NH2:35])[N:9](C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)(OC(C)(C)C)=O.N(CCCI)=[N+]=[N-]>[Pd]>[NH2:35][CH2:34][CH2:33][CH2:32][NH:31][CH2:30][CH2:29][CH2:28][CH2:27][NH:26][CH2:25][CH2:24][CH2:8][NH2:9]

Komponenten

4

Edukt 2

HCID 10910823HCID 10910823, VerbindungHCID 22610912TriBoc-Spermine

Produkt 1

HCID 1103Spermine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

Monoquaternary spermine containing hydrophilic head-group was prepared in a similar way to compound 3. Briefly, TriBoc-Spermine was reacted with excess of 1-azido-3-iodo-propane in the presence of excess TBA. The resulting quaternarized derivative was hydrogenised under (Pd—C) and Boc protecting group were removed using gaseous HCl in dry methanol.

Aufarbeitung

  1. customwere removed

Quellen und Nachweise

ORD-Eintrag
ord-7efc57ded6f7404794f1c0a62996d328
Quelldatensatz
uspto-grants-2005_10
Patentnummer
US06958325B2

Verknüpfte Notizen

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