Sodium Methoxide → HCID 54545679, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][N:10]=2)[N:5]([C@@H:12]2[O:26][C@H:25]([CH2:27][O:28]C(C3C(C)=CC=CC=3)=O)[C@@H:14]([O:15]C(C3C(C)=CC=CC=3)=O)[CH2:13]2)[C:4](=[O:38])[N:3]=1.C[O-].[Na+]>CC(O)=O>[NH2:1][C:2]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][N:10]=2)[N:5]([C@@H:12]2[O:26][C@H:25]([CH2:27][OH:28])[C@@H:14]([OH:15])[CH2:13]2)[C:4](=[O:38])[N:3]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To 0.51 g (1 mmole) of 4-amino-1-(2-deoxy-3,5-di-O-toluoyl-β-D-ribofuranosyl)-pteridine-2-one (31) is added 50 mL of 0.0005N sodium methoxide. The mixture is stirred at room temperature for 24 h. The mixture is then neutralized with AcOH, evaporated to dryness, and twice coevaporated with H2O. The residue is then recrystallized from 50 mL of ethanol to give 32.