Pinacolone → 1-Hydroxy-4,4-dimethylpent-1-en-3-one

HRID 986464

Reaktionsgleichung

Reaktionsgleichung von HRID 986464
[CH3:1][C:2](=[O:7])[C:3]([CH3:6])([CH3:5])[CH3:4].[CH:8](OC)=[O:9]>C(OCC)C>[CH3:4][C:3]([CH3:6])([CH3:5])[C:2](=[O:7])[CH:1]=[CH:8][OH:9]

Komponenten

4

Edukt 2

HCID 6416PinacoloneHCID 7865Methyl formate

Produkt 1

HCID 405073641-Hydroxy-4,4-dimethylpent-1-en-3-oneAusbeute 97,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Reaktionsbedingungen

Temperatur
30 °C

Versuchsvorschrift

56.0 g (0.5 mole) of potassium tert.-butylate are added to a mixture of 50.0 g (0.5 mole) of pinacolone and 42.0 g (0.5 mole) of methyl formate at 15° to 20° C., with cooling. The reaction mixture is subsequently stirred at 30° C. for 12 hours. For working up, 400 ml of diethyl ether are added and the product precipitated is filtered off with suction and dried. 62.3 g (75% of theory) of 4,4-dimethyl-1-hydroxy-1-penten-3-one, as the potassium salt, are obtained in the form of a light yellow powder.

Aufarbeitung

  1. temperaturewith cooling
  2. customthe product precipitated
  3. filtrationis filtered off with suction
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e361deaaf8ae41729c3041dd70f2be84
Quelldatensatz
uspto-grants-1987_12
Patentnummer
US04713456

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