Nitric Acid → 1-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane

HRID 990070

Reaktionsgleichung

Reaktionsgleichung von HRID 990070
[C:1]([O:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]2[O:13][CH2:14][O:15][C:9]=2[CH:8]=1)(=[O:3])[CH3:2].[N+:16]([O-])([OH:18])=[O:17].O>C(O)(=O)C>[C:1]([O:4][CH2:5][CH2:6][C:7]1[C:12]([N+:16]([O-:18])=[O:17])=[CH:11][C:10]2[O:13][CH2:14][O:15][C:9]=2[CH:8]=1)(=[O:3])[CH3:2]

Komponenten

5

Edukt 3

HCID 944Nitric AcidHCID 962WaterHCID 3030742-(1,3-Benzodioxol-5-yl)ethyl acetate

Produkt 1

HCID 234454281-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethaneAusbeute 88 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

To a stirred solution of 1-acetoxy-2-[(3,4-methylenedioxy)-phenyl]ethane (1.7 g, 8.09 mmol) in acetic acid (10 mL) was added, dropwise, concentrated HNO3 (4.5 mL). This was stirred at room temperature for 30 min. The reaction mixture was poured into water (100 mL). The precipitated solid was filtered, washed with water and dried under high vacuum to afford 1-acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane (1.8 g, 88% yield).

Aufarbeitung

  1. filtrationThe precipitated solid was filtered
  2. washwashed with water
  3. customdried under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-bc49a2cc0b734445bb4df2f685fd3820
Quelldatensatz
uspto-grants-2002_10
Patentnummer
US06458805B2

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