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o-CRESYL GLYCIDYL ETHER

HCID 16640
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Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
2210-79-9
Standard SMILES
Cc1ccccc1OCC1CO1
InChIKey
KFUSXMDYOPXKKT-UHFFFAOYSA-N
Molecular formula
C10H12O2
Average molar mass
164.2 g/mol
Monoisotopic mass
164.08372962

Overview

O-cresyl glycidyl ether is a clear light yellow liquid. (NTP, 1992)

Names & identifiers

Preferred name
o-CRESYL GLYCIDYL ETHER
IUPAC
2-[(2-methylphenoxy)methyl]oxirane
English name
2-[(2-Methylphenoxy)methyl]oxirane
Molecular formula
C10H12O2
Molecular weight
164.2

Names & synonyms

2210-79-9O-CRESYL GLYCIDYL ETHERGlycidyl 2-methylphenyl etherGlycidyl o-tolyl ether2-Methylphenyl glycidyl etherAraldite DY 0231,2-Epoxy-3-(2-methylphenoxy)propane1-(2-Methylphenoxy)-2,3-epoxypropaneDTXSID80248621-(o-Methylphenoxy)-2,3-epoxypropane((2-Methylphenoxy)methyl)oxirane1,2-Epoxy-3-(o-tolyloxy)propane
Show more names
DY 023Nsc11571o-cresylHeloxy 62Epodil 742aralditedy0232-((o-Tolyloxy)o-Cresolglycidylethero-Kresol-glycidaether
Glycidyl o-methylphenyl etherPropane, 1,2-epoxy-3-(o-tolyloxy)-Oxirane, ((2-methylphenoxy)methyl)-(2-Methylphenoxymethyl)oxirane2,3-Epoxypropyl o-tolyl etherNSC-11571NSC-20291Oxirane, [(2-methylphenoxy)methyl]-

Database identifiers

CAS
2210-79-9
PubChem CID
16640
DTXSID
DTXSID8024862
ChEMBL
CHEMBL1445408
UNII
8Z744RD471
EC Number
218-645-3
Nikkaji
J475.256B、J59.926C

Properties

Computed structural propertiesFilling in

XLogP
2.4
Topological polar surface area
21.8 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
2
Rotatable bonds
3
Heavy atoms
12
Formal charge
0
Complexity
147

Experimental & physicochemical properties

PolymersPlastics & Rubber -> Glycidyl Ethers
Density · 2 items

1.09 at 68 °F (NTP, 1992) - Denser than water; will sink

Relative density (water = 1): 1.08

Solubility · 2 items

less than 1 mg/mL at 72 °F (NTP, 1992)

Solubility in water: none

Flash Point · 3 items

200 °F (NTP, 1992)

200 °F

113 °C c.c.

Boiling Point · 2 items

498 °F at 760 mmHg (NTP, 1992)

at 0.533kPa: 109-111 °C

Vapor DensityRelative vapor density (air = 1): 5.7
Physical Description · 4 items

O-cresyl glycidyl ether is a clear light yellow liquid. (NTP, 1992)

Liquid

Clear light yellow liquid; [CAMEO]

COLOURLESS LIQUID.

Physicochemical properties

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 6 items

Warning

H315: Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P272, P273, P280, P302+P352, P318, P321, P332+P317, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P272, P273, P280, P302+P352, P318, P321, P332+P317, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)

Hazard information

Regulatory Information · 5 items

Chemical: Oxirane, [(2-methylphenoxy)methyl]-

Oxirane, 2-[(2-methylphenoxy)methyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-[(2-methylphenoxy)methyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.

Status: Active Update: 05-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14553

Oxirane, [(2-methylphenoxy)methyl]-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Oxirane, [(2-methylphenoxy)methyl]-: Environment tier I assessment
DOT LabelClass 9
Fire Hazards · 2 items

This chemical is combustible. (NTP, 1992)

Combustible.

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and eyes, and allergic dermatitis.

Chemistry & industry

Uses & manufacturing

Uses · 2 items

Glycidyl ethers are used as reactive diluents in epoxy resins. [LaDou, p. 550]

Plastic Composites Manufacturing [Category: Industry]

U.S. Production2023: 250,000 - <400,000 lb
Consumer UsesViscosity modifiers
Industry UsesDiluent
Household ProductsInformation on 3 consumer products that contain O-Cresyl glycidyl ether in the following categories is provided:
General Manufacturing Information · 2 items

Custom Compounding of Purchased Resins

Oxirane, 2-[(2-methylphenoxy)methyl]-: ACTIVE

Applications

General DescriptionClear light yellow liquid.

Related reactions

20 records
New reaction record
HRID 98643 reaction equation
HRID 98643As reactantTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
HRID 111813 reaction equation
HRID 111813As reactantTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
HRID 224893 reaction equation
HRID 224893As reactantuspto-grants-1980_11
HRID 224894 reaction equation
HRID 224894As reactantuspto-grants-1980_11
HRID 239022 reaction equation
HRID 239022As reactantuspto-grants-2014_02
HRID 728836 reaction equation
HRID 728836As reactantuspto-grants-1991_09
HRID 745506 reaction equation
HRID 745506As reactantuspto-grants-1986_07
HRID 745507 reaction equation
HRID 745507As reactantuspto-grants-1986_07
Page 1 of 3

Compound notes

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On this pageBasic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Boiling point
109 · 109-111 °C/4 mmHg (lit.)
Density
1.079 g/mL · 1.079 g/mL at 25 °C (lit.)
vapor density
1 · >1 (vs air)
vapor pressure
0.514 Pa · 0.514Pa at 20℃
refractive index
20 · n20/D 1.529(lit.)
Flash point
230 °F · >230 °F
form
liquid
Water Solubility
840 mg/L · 840mg/L at 21℃
BRN
4585 · 4585
InChI
InChI=1S/C10H12O2/c1-8-4-2-3-5-10(8)12-7-9-6-11-9/h2-5,9H,6-7H2,1H3
InChIKey
KFUSXMDYOPXKKT-UHFFFAOYSA-N
SMILES
O1CC1COC1=CC=CC=C1C
LogP
2.5 at · 2.5 at 21℃
CAS DataBase Reference
2210 · 2210-79-9(CAS DataBase Reference)
EWG's Food Scores
2 · 2-3
FDA UNII
8 Z744RD471 · 8Z744RD471
NIST Chemistry Reference
Oxirane, [(2-methylphenoxy)methyl]-(2210-79-9)
EPA Substance Registry System
o-Cresyl glycidyl ether (2210-79-9)
UNSPSC Code
12162002 · 12162002
NACRES
23 · NA.23
Symbol(GHS)
7 · GHS07,GHS08,GHS09
Signal word
Warning
Hazard statements
315 · H315-H317-H341-H411
Precautionary statements
202 · P202-P261-P273-P280-P302+P352-P308+P313
PPE
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes
Xi,N,Xn
Risk Statements
36 · 36/37/38-68-51/53-43-38
Safety Statements
26 · 26-37/39-61-36/37
RIDADR
3082 · UN 3082 9/PG 3
WGK Germany
2 · 2
RTECS
3700000 · TZ3700000
TSCA
TSCA listed
HazardClass
9 · 9
PackingGroup
III
HS Code
29109000 · 29109000
Storage Class
10 · 10 - Combustible liquids
Hazard Classifications
2 Muta · Aquatic Chronic 2Muta. 2Skin Irrit. 2Skin Sens. 1A
REACH Registrations
Active
Hazards SummaryMay cause skin sensitization; [ICSC] Danger of skin sensitization; [MAK]
Reactive GroupEthers
EC ClassificationSymbol: Xn, N; R: 38-43-68-51/53; S: (2)-36/37-61; Note: C
Reactivity ProfileO-CRESYL GLYCIDYL ETHER may attack some forms of plastics. (NTP, 1992)
Chemical DangersThe substance can presumably form explosive peroxides. Reacts with acids, amines, bases and strong oxidants.
Air and Water ReactionsInsoluble in water.
Hazard Classes and Categories · 6 items

Skin Irrit. 2 (100%)

Skin irritation - category 2

Serious eye damage/eye irritation - Category 2B

Skin sensitization - Category 1A

Skin corrosion/irritation - Category 2

Muta. 2

Safety & protection

Fire Fighting · 2 items

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

Use water spray, foam, powder, carbon dioxide.

First Aid Measures · 4 items

Fresh air, rest.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Safe StorageSeparated from strong oxidants, strong bases, strong acids and amines. Cool. Keep in the dark.
Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Spillage Disposal · 1 item

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Isolation and EvacuationExcerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:
Eye PreventionWear safety goggles or eye protection in combination with breathing protection.
Fire PreventionNO open flames.
Inhalation RiskNo indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
Skin PreventionProtective gloves. Protective clothing.
Exposure PreventionAVOID ALL CONTACT!

Toxicology

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.
Signs and Symptoms · 3 items

Cough. Sore throat.

Redness. Pain.

Redness.

Toxicity DataLC50 (rat) = 6,090 mg/m3/4h

Safety data

PPE
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk
2
tsca
TSCA listed
rtecs
TZ3700000
ridadr
UN 3082 9/PG 3
hs_code
29109000
risk_code
36/37/38-68-51/53-43-38
Signal word
Warning
Symbol(GHS)
GHS07,GHS08,GHS09
hazard_code
Xi,N,Xn
safety_code
26-37/39-61-36/37
hazard_class
9
Storage Class
10 - Combustible liquids
packing_group
III
Hazard statements
H315-H317-H341-H411
REACH Registrations
Active
Hazard Classifications
Aquatic Chronic 2Muta. 2Skin Irrit. 2Skin Sens. 1A
Precautionary statements
P202-P261-P273-P280-P302+P352-P308+P313