CAS 3179-76-8 3-(Diethoxymethylsilyl)propylamine (HCID 18511)

Names & identifiers

Preferred name: 3-(Diethoxymethylsilyl)propylamine
IUPAC: 3-[diethoxy(methyl)silyl]propan-1-amine
English name: 3-Aminopropyl-methyl-diethoxysilane
Molecular formula: C8H21NO2Si
Molecular weight: 191.34

Names & synonyms

3179-76-83-(Diethoxymethylsilyl)propylamineDynasylan 15061-Propanamine, 3-(diethoxymethylsilyl)-Dynasylan 1505(3-Aminopropyl)diethoxymethylsilaneKBE 902gamma-AminopropylmethyldiethoxysilanePROPYLAMINE, 3-(DIETHOXYMETHYLSILYL)-Silane, (3-aminopropyl)diethoxymethyl-A36TO38MQNEINECS 221-660-8

Show more names

KH-9023-AMINOPROPYLMETHYLDIETHOXYSILANEkbe902CA0742A-1505dynasylan1506dynasylan15053-Aminopropyl-methyl

BRN 1744264(3-Aminopropyl)methyldiethoxysilaneEC 221-660-84-04-00-04201 (Beilstein Handbook Reference)(aminopropyl)methyldiethoxysilane.GAMMA.-DIETHOXYMETHYLSILYLPROPYLAMINE.GAMMA.-AMINOPROPYLMETHYLDIETHOXYSILANE3propan1amine

Database identifiers

CAS: 3179-76-8
PubChem CID: 18511
DTXSID: DTXSID2038817
UNII: A36TO38MQN
EC Number: 221-660-8
Nikkaji: J21.114A

Properties

Computed structural properties

Topological polar surface area: 44.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 7
Heavy atoms: 12
Formal charge: 0
Complexity: 105

Experimental & physicochemical properties

Chemical ClassesMetals -> Metalloid Compounds (Silicon)

Density0.94 @25 °C

Boiling Point200 °C @760 [mm Hg]

Vapor Pressure0.1 [mm Hg] @20 °C

Physical DescriptionLiquid

Physicochemical properties

Melting point: -20 °C · <-20°C
Boiling point: 85 · 85-88 °C8 mm Hg(lit.)
Density: 0.916 g/mL · 0.916 g/mL at 25 °C(lit.)
vapor pressure: 6.9 Pa · 6.9Pa at 25℃
refractive index: 20 · n20/D 1.426(lit.)
Flash point: 168 °F · 168 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: liquid
pka: 10.52 · 10.52±0.10(Predicted)
Specific Gravity: 0.916 · 0.916
color: Colorless to Almost colorless
Water Solubility: Soluble and reacts with water.
Hydrolytic Sensitivity: 7 · 7: reacts slowly with moisture/water
Sensitive: Air & Moisture Sensitive
BRN: 1744264 · 1744264
InChI: 1S/C8H21NO2Si/c1-4-10-12(3,11-5-2)8-6-7-9/h4-9H2,1-3H3
InChIKey: HXLAEGYMDGUSBD-UHFFFAOYSA-N
SMILES: CCO[Si](C)(CCCN)OCC
LogP: 2.5 at · 2.5 at 20℃
CAS DataBase Reference: 3179 · 3179-76-8(CAS DataBase Reference)
EWG's Food Scores: 1 · 1
FDA UNII: 36 TO38MQN · A36TO38MQN
NIST Chemistry Reference: 1 · 1-Propanamine, 3-(diethoxymethylsilyl)-(3179-76-8)
EPA Substance Registry System: 1 · 1-Propanamine, 3-(diethoxymethylsilyl)- (3179-76-8)
UNSPSC Code: 12352103 · 12352103
NACRES: 23 · NA.23
Symbol(GHS): 5 · GHS05
Signal word: Danger
Hazard statements: 314 · H314
Precautionary statements: 280 · P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C
Risk Statements: 34 · 34
Safety Statements: 26 · 26-36/37/39-45
RIDADR: 3267 · UN 3267 8/PG 2
WGK Germany: 3 · 3
RTECS: 700000 · UI0700000
F: 10 · 10-21-34
TSCA: TSCA listed
HazardClass: 8 · 8
PackingGroup: III
HS Code: 29319090 · 29319090
Storage Class: 8 A · 8A - Combustible corrosive hazardous materials
Hazard Classifications: 1 B · Skin Corr. 1B
Toxicity: 50 oral · LD50 oral in rat: 4760uL/kg
REACH Registrations: Active
Limited Quantities: 1 L · 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 1.7% (5 of 299) of reports.

Danger

H314 (91%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 299 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 4 items

Chemical: 1-Propanamine, 3-(diethoxymethylsilyl)-

1-Propanamine, 3-(diethoxymethylsilyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Propanamine, 3-(diethoxymethylsilyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 13-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5328

1-Propanamine, 3-(diethoxymethylsilyl)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryA mild skin irritant; Oral LD50 (rat) = 4.76 mL/kg; Dermal LD50 (rabbit) = 2.52 mL/kg; [RTECS] Reacts with water; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS]

Hazard Classes and CategoriesSkin Corr. 1B (91%)

Safety & protection

Protective Action Criteria (PAC) · 3 items

13 [mg/m3]

140 [mg/m3]

860 [mg/m3]

Toxicology

Adverse EffectsDermatotoxin - Skin burns.

Safety data

F: 10-21-34
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
rtecs: UI0700000
ridadr: UN 3267 8/PG 2
hs_code: 29319090
Toxicity: LD50 oral in rat: 4760uL/kg
risk_code: 34
Signal word: Danger
Symbol(GHS): GHS05
hazard_code: C
safety_code: 26-36/37/39-45
hazard_class: 8
Storage Class: 8A - Combustible corrosive hazardous materials
packing_group: III
Hazard statements: H314
Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
REACH Registrations: Active
Hazard Classifications: Skin Corr. 1B
Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

Chemistry & industry

Uses & manufacturing

Uses · 2 items

Used to formulate coatings, paints, thinners, paint removers, adhesives, and sealants, in polymer preparations and compounds, as a chemical intermediate, and as a laboratory reagent; [ExPub: ECHA REACH Registrations]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

U.S. Production2023: <50,000 lb

Industry UsesMonomers

General Manufacturing Information · 2 items

All Other Basic Inorganic Chemical Manufacturing

1-Propanamine, 3-(diethoxymethylsilyl)-: ACTIVE

Applications

Uses(3-Aminopropyl)diethoxymethylsilane is used as silane coupling agent. The aromatic imine monolayers were prepared by reacting (3-aminopropyl)diethoxymethylsilane.