Basic information
- CAS
2418-95-3- Standard SMILES
CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)O- InChIKey
VVQIIIAZJXTLRE-QMMMGPOBSA-N- Molecular formula
- C11H22N2O4
- Average molar mass
- 246.3 g/mol
Overview
N6-(tert-Butoxycarbonyl)-L-lysine (BocLys) is an organic molecular entity.
Names & identifiers
- Preferred name
- (2S)-2-amino-6-(((tert-butoxy)carbonyl)amino)hexanoic acid
- IUPAC
- (2S)-2-amino-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
- English name
- H-Lys(Boc)-OH
- Molecular formula
- C11H22N2O4
- Molecular weight
- 246.3
Names & synonyms
(2S)-2-amino-6-{[(tert-butoxy)carbonyl]amino}hexanoic acid(2S)-2-amino-6-(((tert-butoxy)carbonyl)amino)hexanoic acidRefChem:398350690-500-0H-Lys(Boc)-OHN6-(tert-butoxycarbonyl)-L-lysineLys(Boc)Nepsilon-Boc-L-lysineNe-Boc-L-lysineN6-Boc-L-lysineNepsilon-(tert-Butoxycarbonyl)-L-lysineN~6~-(Tert-Butoxycarbonyl)-L-Lysine
Show more names
Lys(Boc)-OHL-LYS(BOC)L-LYSINE(BOC)H-L-LYS(BOC)-OHNepsilon LLYSINE(BOC)-OH
(S)-2-Amino-6-((tert-butoxycarbonyl)amino)hexanoic acidMFCD00037221(2S)-2-Amino-6-(tert-butoxycarbonylamino)hexanoic acidN?-Boc-L-lysine89054-49-9N(epsilon)-tert-Butoxycarbonyl-L-lysine(2S)-2-amino-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acidL-lysine, N~6~-[(1,1-dimethylethoxy)carbonyl]-
Database identifiers
- CAS
2418-95-3- PubChem CID
Properties
Computed structural properties
- XLogP
- -1.6
- Topological polar surface area
- 102 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 8
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 261
Physicochemical properties
- Melting point
- 250 °C · 250 °C (dec.)(lit.)
- alpha
- 17 · 17 º (c=1% in acetic acid)
- Boiling point
- 389.3 °C · 389.3°C (rough estimate)
- Density
- 1.1313 · 1.1313 (rough estimate)
- refractive index
- 18 ° · 18 ° (C=1, AcOH)
- storage temp.
- 2 · 2-8°C
- solubility
- Soluble in DMSO
- form
- powder to crystal
- pka
- 2.53 · 2.53±0.24(Predicted)
- color
- White to Almost white
- optical activity
- 20 · [α]20/D +18°, c = 1 in acetic acid
- Water Solubility
- Slightly soluble in water.
- BRN
- 2417626 · 2417626
- Major Application
- peptide synthesis
- InChI
- 1S/C11H22N2O4/c1-11(2,3)17-10(16)13-7-5-4-6-8(12)9(14)15/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
Safety & regulation
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- hs_code
- 29241990
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P301+P312-P362+P364
Chemistry & industry
Applications
UsesIt is used as therapy to treat recurrent herpes simplex infections.
General DescriptionH-Lys(Boc)-OH, also known as H-Lys(t-BOC)-OH, is an ε-amino-protected lysine. Its e-amino free lysine could be conjugated to polyurethane surfaces by reaction of the alpha-amino group with the NHS and deprotection. The covalent conjugation was carried out in phosphate-buffered saline (PBS), pH 8.2. Lysine was used to create a plasminogen-binding potentially fibrinolytic surface[1].
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers101 total
北京华美互利生物化工010-56205725 · [email protected]
Related reactions
18 records
Compound notes
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