Hexadecylamine

HCID 8926CAS 143-27-1

Basic information

Standard SMILES
CCCCCCCCCCCCCCCCN
InChIKey
FJLUATLTXUNBOT-UHFFFAOYSA-N
Molecular formula
C16H35N
Average molar mass
241.46 g/mol
Monoisotopic mass
241.27695012

Overview

Hexadecylamine is a white solid. (NTP, 1992)

Names & identifiers

Preferred name
Hexadecylamine
IUPAC
hexadecan-1-amine
English name
1-Hexadecylamine
Molecular formula
C16H35N
Molecular weight
241.46

Names & synonyms

Hexadecylamine1-HexadecylamineCetylamine143-27-1hexadecan-1-amine1-Hexadecanamine1-AminohexadecaneN-HEXADECYLAMINEPalmitaminen-CetylamineHexyldecylaminePalmitylamine
Show more names
HDAHADArmeen 16
Armeen 16DMonohexadecylamineAlamine 6Palmityl amineNissan amine PBCetylaminAlamine 6D1-Hexadecanylamine

Database identifiers

CAS
143-27-1、68037-95-6
PubChem CID
8926
DTXSID
DTXSID7025390
ChEMBL
CHEMBL1534653
ChEBI
CHEBI:165594
UNII
O2H0Q02M4P
EC Number
205-596-8
Nikkaji
J6.125E

Properties

Computed structural properties

XLogP
7.4
Topological polar surface area
26 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
1
Rotatable bonds
14
Heavy atoms
17

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
CosmeticsAntistatic
SpringerMaterials PropertiesBoiling point
Density · 2 items

0.8129 at 68 °F (NTP, 1992) - Less dense than water; will float

0.8129 @ 20°C

Solubilityless than 1 mg/mL at 72 °F (NTP, 1992)
Flash Point285 °F (NTP, 1992)

Physicochemical properties

Melting point
43 · 43-45 °C (lit.)
Boiling point
330 °C · 330 °C (lit.)
Density
0 · 0,813 g/cm3
vapor pressure
1 mm · <1 mm Hg ( 20 °C)
refractive index
1.4496 · 1.4496
Flash point
285 °F · 285 °F

Safety & regulation

GHS classification

GHS Classification · 6 items

Danger

H314 (98%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P273, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 50 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

Hazard information

Regulatory Information · 3 items

Chemical: 1-Hexadecanamine

Status: Active Update: 30-09-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/29504

Hexadecylamine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Primary aliphatic (C12-22) and fatty amines: Human health tier II assessment
DOT LabelCorrosive
Fire HazardsThis chemical is combustible. (NTP, 1992)
Health HazardsExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Hazards SummaryMay cause skin, eye, and mucous membrane irritation; [CAMEO] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS] See Decylamine.

Safety & protection

Fire FightingFires involving this chemical can be controlled with a CO2, dry chemical, or Halon extinguisher. (NTP, 1992)
First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Protective Action Criteria (PAC) · 3 items

0.66 [mg/m3]

7.2 [mg/m3]

43 [mg/m3]

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Toxicology

Adverse EffectsDermatotoxin - Skin burns.

Safety data

F
34
PPE
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
wgk
2
tsca
TSCA listed
rtecs
ML9100000
ridadr
UN 3259 8/PG 2

Chemistry & industry

Uses & manufacturing

UsesUsed to make other chemicals; [CAMEO]
Use ClassificationCosmetics -> Antistatic
General Manufacturing Information1-Hexadecanamine: ACTIVE
Applications · 3 items

UsesDental caries prophylactic.

Uses1-Hexadecylamine is used for producing resin, senior detergent, anti-caking agent.

General DescriptionA white waxy solid with an ammonia-like odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals.

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]

Additional notes

DefinitionChEBI: 1-Hexadecylamine is an alkylamine.

Related reactions

46 records

Linked notes

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