Zinc Hydroxide
Basic information
- CAS
20427-58-1- Standard SMILES
[OH-].[OH-].[Zn+2]- InChIKey
UGZADUVQMDAIAO-UHFFFAOYSA-L- Molecular formula
- H2O2Zn
- Average molar mass
- 99.4 g/mol
- Monoisotopic mass
- 97.934621
Overview
The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Hydroxide...
Names & identifiers
- Preferred name
- Zinc Hydroxide
- IUPAC
- zinc dihydroxide
- English name
- Zinc hydroxide
- Molecular formula
- H2O2Zn
- Molecular weight
- 99.41
Names & synonyms
ZINC HYDROXIDEZinc dihydroxideOXK3V8KJ7LDTXSID7042516RefChem:904951zinc(2+) ion dihydroxideDTXCID5022516243-814-320427-58-1Zinc hydroxide (Zn(OH)2)ZINCHYDROXIDEMFCD00049620
Show more names
znmc hydroxideZinc dihydoxidezincdihydroxidezinchydroxide(zn(oh)2)Zinc oxide ammonia complexZinc hydroxide≥ 99% (Assay)ZINC HYDROXIDE ISO 9001：2015 REACH
Zinc hydroxide [VANDF]SCHEMBL19509AKOS015833777NS00084213F510145Q204820
Database identifiers
- CAS
20427-58-1- PubChem CID
- 9812759
- DTXSID
DTXSID7042516- UNII
- OXK3V8KJ7L
- EC Number
- 243-814-3
- Nikkaji
- J134.217G
Properties
Computed structural properties
- Topological polar surface area
- 2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 3
- Formal charge
- 0
- Complexity
- 0
Experimental & physicochemical properties
Chemical ClassesMetals -> Metals, Inorganic Compounds
CosmeticsCosmetic ingredients (Zinc Hydroxide) -> CIR (Cosmetic Ingredient Review)
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description
Liquid; Wet Solid
Colorless solid; [Hawley] White odorless powder; [MSDSonline]
Physicochemical properties
- Melting point
- 125 · 125, decomposes [HAW93]
- Density
- 3.05 · 3.050
- vapor pressure
- 0 Pa · 0Pa at 20℃
- storage temp.
- Store at room temperature, keep dry and cool
- form
- colorless orthorhombic crystals
- color
- colorless orthorhombic crystals, crystalline
- PH
- 8.88 · 8.88(1 mM solution);8.88(10 mM solution);8.88(100 mM solution)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 3.2% (11 of 348) of reports.
Warning
H315 (18.1%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 348 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Zinc hydroxide (Zn(OH)2)
Zinc hydroxide (Zn(OH)2) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Zinc hydroxide (Zn(OH)2) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Zinc hydroxide (EC: 243-814-3)
Zinc hydroxide: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryAn irritant; [MSDSonline] See Zinc.
Hazard Classes and CategoriesSkin Irrit. 2 (18.1%)
Safety & protection
Exposure Control and Personal Protection0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. cmpnds[German Research Foundation (DFG)]
Minimum Risk LevelIntermediate Oral: 0.3 mg/kg/day (L134)
Chronic Oral: 0.3 mg/kg/day (L134)
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49)
Uses & manufacturing
Uses
CIR ingredient: Zinc Hydroxide
Used in chemical production, surgical dressings (absorbent), and rubber compounding; [Hawley]
Zinc hydroxide is used in surgical dressings. (L68)
U.S. Production2023: 5,000,000 - <10,000,000 lb
Consumer UsesSoil amendments (fertilizers)
Industry UsesOther
General Manufacturing Information
Miscellaneous Manufacturing
Zinc hydroxide (Zn(OH)2): ACTIVE
Applications
DescriptionZinc hydroxide is a white solid that usually forms in solution. It is not very stable as a dried solid, therefore a standard of zinc hydroxide is not available commercially.Zinc hydroxide Zn(OH)2 is an amphoteric chemical compound. Both bases and acids react with zinc hydroxide. It's an insoluble hydroxide that dissolves when exposed to a strong acid. It occurs naturally as the rare minerals Wulfingite, ashoverite and sweetite. Zinc hydroxide is used as a biological absorbant often.
Related reactions
8 records
Compound notes
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