Citric Acid → 5-fluoropyridine-2-carboxylic Acid

HRID 102421

Reaction equation

HRID 102421 reaction equation
[CH3:33][OH:34].[F:3][c:4]1[cH:5][cH:6][c:7]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[n:8][cH:9]1.[Na+:2].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[OH-:1].[OH:15][C:16]([CH2:17][C:18]([C:19](=[O:20])[OH:21])([CH2:22][C:23](=[O:24])[OH:25])[OH:26])=[O:27]>>[F:3][c:4]1[cH:5][cH:6][c:7]([C:10](=[O:11])[OH:12])[n:8][cH:9]1

Participants

7

Reactant 6

HCID 311Citric AcidHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 10986675Ethyl 5-fluoropyridine-2-carboxylate

Product 1

HCID 27628765-fluoropyridine-2-carboxylic Acid

Sources & evidence

ORD record
ord-11f910a522b44ec8b561e768b6944326
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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