Sodium Ion → (2-(1,2-Dimethylpropyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol

Reaction equation

[Al+3:26].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:1][CH:2]([CH:3]([CH3:4])[CH3:5])[c:6]1[c:7](-[c:16]2[c:17]([F:24])[cH:18][cH:19][c:20]([O:22][CH3:23])[cH:21]2)[cH:8][cH:9][c:10]([C:12](=[O:13])[O:14][CH3:15])[cH:11]1.[H-:25].[H-:28].[H-:29].[H-:30].[Li+:27].[Na+:32].[OH-:31]>>[CH3:1][CH:2]([CH:3]([CH3:4])[CH3:5])[c:6]1[c:7](-[c:16]2[c:17]([F:24])[cH:18][cH:19][c:20]([O:22][CH3:23])[cH:21]2)[cH:8][cH:9][c:10]([CH2:12][OH:13])[cH:11]1

Participants

Reactant 7

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 57705901Methyl 2-(1,2-dimethylpropyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate

Product 1

Sources & evidence

ORD record: ord-4d9013d97ba446b9bf58e91da67fafb3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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