Sodium Ion → 5-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

Reaction equation

[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[n:9][cH:10]1.[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[CH:13]([CH3:14])([CH3:15])[Si:16]([CH:17]([CH3:18])[CH3:19])([CH:20]([CH3:21])[CH3:22])[Cl:23].[H-:11].[Na+:12].[OH2:24]>>[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7]([Si:16]([CH:13]([CH3:14])[CH3:15])([CH:17]([CH3:18])[CH3:19])[CH:20]([CH3:21])[CH3:22])[c:8]2[n:9][cH:10]1

Participants

Reactant 6

HCID 923Sodium Ion

HCID 962Water

HCID 6228Dimethylformamide

HCID 139400Triisopropylsilyl chloride

HCID 166653Hydride

HCID 103079325-bromo-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 242292235-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record: ord-c0126ac92ce5496fb1b54a6cad32f752
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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