Acetic Acid → 2-Bromo-6-fluorobenzaldehyde

HRID 104954

Reaction equation

HRID 104954 reaction equation
[Br:13][c:14]1[cH:15][c:16]([F:20])[cH:17][cH:18][cH:19]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:21][N:22]([CH:23]=[O:24])[CH3:25].[CH3:32][C:33](=[O:34])[OH:35].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[OH2:31]>>[Br:13][c:14]1[c:15]([CH:23]=[O:24])[c:16]([F:20])[cH:17][cH:18][cH:19]1

Participants

8

Reactant 7

HCID 176Acetic AcidHCID 962WaterHCID 6228DimethylformamideHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 140821-Bromo-3-fluorobenzeneHCID 178418339Butyllithium

Product 1

HCID 224739772-Bromo-6-fluorobenzaldehyde

Sources & evidence

ORD record
ord-e4fe2e1a75694b158ae1c1788c2e317b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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