Triethylamine → HCID 14853717, compound
Reaction equation
[NH2:1][C:2]1[C:3]([NH:8][CH:9]([CH3:11])[CH3:10])=[N:4][CH:5]=[CH:6][CH:7]=1.C(N(CC)CC)C.[C:19](Cl)([C:21](OCC)=[O:22])=[O:20]>O1CCCC1>[CH:9]([N:8]1[C:19](=[O:20])[C:21](=[O:22])[NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[N:4][C:3]1=2)([CH3:11])[CH3:10]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a stirred solution of 3-amino-2-isopropylamino-pyridine (2.0 g, 10.6 mmole) and triethylamine (4.8 ml, 34.6 mmole) in tetrahydrofuran (30 ml) was dropwise added ethoxalyl chloride (2.68 ml, 24 mmole). Stirring was continued for two hours after the addition. The mixture was filtered through a glass filter funnel and the filtrate was evaporated to give the title compound as white crystals. M.p. 246°-247° C.
Workup
- additionafter the addition
- filtrationThe mixture was filtered through a glass
- filtrationfilter funnel
- customthe filtrate was evaporated
Sources & evidence
- ORD record
- ord-c3efe739163c4d1384777b2d237f57ca
- Source dataset
- uspto-grants-1990_11
- Patent number
- US04968682
Reaction notes
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