Tetrahydrofuran → 5-chloro-2-methoxy-N-[5-methyl-3-(oxolan-2-ylmethyl)-1,3-thiazol-2-ylidene]benzamide

HRID 107777

Reaction equation

HRID 107777 reaction equation
[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:29][c:30]1[cH:31][n:32]([CH2:36][CH:37]2[O:38][CH2:39][CH2:40][CH2:41]2)[c:33](=[NH:35])[s:34]1.[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[Cl:13][c:14]1[cH:15][cH:16][c:17]([O:18][CH3:19])[c:20]([C:22]([Cl:23])=[O:24])[cH:21]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH3:12])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[S:25]([Cl:26])([Cl:27])=[O:28]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH3:12])[c:6]([C:7](=[O:9])[N:35]=[c:33]2[n:32]([CH2:36][CH:37]3[O:38][CH2:39][CH2:40][CH2:41]3)[cH:31][c:30]([CH3:29])[s:34]2)[cH:10]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 24386Thionyl ChlorideHCID 769705-Chloro-o-anisic acidHCID 123841765-Chloro-2-methoxybenzoyl chlorideHCID 668516985-methyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

Product 1

HCID 248980645-chloro-2-methoxy-N-[5-methyl-3-(oxolan-2-ylmethyl)-1,3-thiazol-2-ylidene]benzamide

Sources & evidence

ORD record
ord-512b7d1ab8ae431d9304aa6a429eb304
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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