Diethyl Carbonate → 4-(Methoxymethyl)-1,3-dioxolan-2-one

Reaction equation

[CH3:1][O:2][CH2:3][CH:4]([OH:7])[CH2:5][OH:6].[C:8](=O)(OCC)[O:9]CC.[H-].[Na+]>>[CH3:1][O:2][CH2:3][CH:4]1[CH2:5][O:6][C:8](=[O:9])[O:7]1

Participants

Reactant 3

HCID 7766Diethyl Carbonate

HCID 24758Sodium hydride

HCID 928223-Methoxy-1,2-propanediol

Product 1

HCID 43844854-(Methoxymethyl)-1,3-dioxolan-2-one

Procedure

A mixture of 14 g (0.132 mol) of compound 370487 (Method 2--Step 2), 31.16 g (0.264 mol) of diethyl carbonate in the presence of 0.108 g of 50% sodium hydride is heated until distillation of the alcohol formed. After completion of the reaction, the aimed product is distilled.