Hydrochloric Acid → N-[[[1-Azabicyclo[2.2.2]octan-3-yl]amino]carbonyl]-2-thiophenecarboxamide

HRID 109441

Reaction equation

HRID 109441 reaction equation
[C:32]([O-:33])(=[O:34])[CH:35]=[CH:36][C:37]([O-:38])=[O:39].[CH:23]([N:24]([CH:25]([CH3:26])[CH3:27])[CH2:28][CH3:29])([CH3:30])[CH3:31].[ClH:1].[ClH:2].[NH2:3][CH:4]1[CH2:5][N:6]2[CH2:7][CH2:8][CH:9]1[CH2:10][CH2:11]2.[cH:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1.[s:12]1[c:13]([C:17](=[O:18])[NH:19][C:20](=[O:21])[NH2:22])[cH:14][cH:15][cH:16]1>>[NH:3]([CH:4]1[CH2:5][N:6]2[CH2:7][CH2:8][CH:9]1[CH2:10][CH2:11]2)[C:20]([NH:19][C:17]([c:13]1[s:12][cH:16][cH:15][cH:14]1)=[O:18])=[O:21]

Participants

7

Reactant 6

HCID 313Hydrochloric Acid2×HCID 1049PyridineHCID 81531DiisopropylethylamineHCID 1232383-AminoquinuclidineHCID 164547ButenedioateHCID 395032N-(Aminocarbonyl)-2-thiophenecarboxamide

Product 1

HCID 15616403N-[[[1-Azabicyclo[2.2.2]octan-3-yl]amino]carbonyl]-2-thiophenecarboxamide

Sources & evidence

ORD record
ord-f33dd8d935194bc2911afefed6b9ca2f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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