Dichloromethane → 2,2-Dimethyl-3-(4-pyridyl)-3-(p-tolylsulfonyloxy)propionitrile

HRID 110816

Reaction equation

HRID 110816 reaction equation
[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:32][CH2:33][Cl:34].[OH:8][CH:9]([C:10]([C:11]#[N:12])([CH3:13])[CH3:14])[c:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1.[c:21]1([CH3:31])[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[Cl:30])[cH:25][cH:26]1>>[O:8]([CH:9]([C:10]([C:11]#[N:12])([CH3:13])[CH3:14])[c:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1)[S:27]([c:24]1[cH:23][cH:22][c:21]([CH3:31])[cH:26][cH:25]1)(=[O:28])=[O:29]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 73974-Toluenesulfonyl chlorideHCID 8471TriethylamineHCID 111376563-Hydroxy-2,2-dimethyl-3-(4-pyridyl)propionitrile

Product 1

HCID 219740222,2-Dimethyl-3-(4-pyridyl)-3-(p-tolylsulfonyloxy)propionitrile

Sources & evidence

ORD record
ord-67118134ee414dfb8d526ea779e168f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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