Pyridine → Flusulfamide

Reaction equation

[CH3:1][c:2]1[c:3]([CH3:4])[cH:5][cH:6][cH:7][cH:8]1.[Cl:20][c:21]1[c:22]([C:31]([F:32])([F:33])[F:34])[cH:23][c:24]([S:27](=[O:28])(=[O:29])[Cl:30])[cH:25][cH:26]1.[Cl:9][c:10]1[c:11]([NH2:12])[cH:13][cH:14][c:15]([N+:17](=[O:18])[O-:19])[cH:16]1.[cH:35]1[cH:36][cH:37][n:38][cH:39][cH:40]1>>[Cl:9][c:10]1[c:11]([NH:12][S:27]([c:24]2[cH:23][c:22]([C:31]([F:32])([F:33])[F:34])[c:21]([Cl:20])[cH:26][cH:25]2)(=[O:28])=[O:29])[cH:13][cH:14][c:15]([N+:17](=[O:18])[O-:19])[cH:16]1

Participants

Reactant 4

HCID 1049Pyridine

HCID 7237O-Xylene

HCID 84922-Chloro-4-nitroaniline

HCID 27807194-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride

Product 1

HCID 86268Flusulfamide

Sources & evidence

ORD record: ord-0cbdc6790e404a87991044a8d50df5f6
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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