2,3-Dichloropyridine → 6-(3-Chloropyridin-2-yl)-5,6,7,8-tetrahydro-N-phenylpyrido[4,3-d]pyrimidin-4-amine

HRID 1114819

Reaction equation

HRID 1114819 reaction equation
[CH3:35][N:36]([CH3:37])[C:38](=[O:39])[CH3:40].[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:18][c:19]1[n:20][cH:21][cH:22][cH:23][c:24]1[Cl:25].[O:41]1[CH2:42][CH2:43][O:44][CH2:45][CH2:46]1.[c:1]1([NH:7][c:8]2[c:9]3[c:10]([n:11][cH:12][n:13]2)[CH2:14][CH2:15][NH:16][CH2:17]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([NH:7][c:8]2[c:9]3[c:10]([n:11][cH:12][n:13]2)[CH2:14][CH2:15][N:16]([c:19]2[n:20][cH:21][cH:22][cH:23][c:24]2[Cl:25])[CH2:17]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 169882,3-DichloropyridineHCID 312751,4-DioxaneHCID 31374DimethylacetamideHCID 81531DiisopropylethylamineHCID 593465585,6,7,8-Tetrahydro-N-phenylpyrido[4,3-d]pyrimidin-4-amine

Product 1

HCID 593464736-(3-Chloropyridin-2-yl)-5,6,7,8-tetrahydro-N-phenylpyrido[4,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-3c00f766b1af4930bc0f1fe0c9c1bd8b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

Loading…