Tetrahydrofuran → N-[1-(5-{3-[(4-cyclopropylpyrimidin-2-yl)amino]-5-methylphenyl}-1,3-thiazol-2-yl)cyclobutyl]-2-methylpropane-2-sulfinamide
Reaction equation
[C:31]1(=[N:35][S:36](=[O:37])[C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:32][CH2:33][CH2:34]1.[CH3:24][CH:25]([N-:26][CH:27]([CH3:28])[CH3:29])[CH3:30].[CH:1]1([c:4]2[n:5][c:6]([NH:10][c:11]3[cH:12][c:13]([CH3:22])[cH:14][c:15](-[c:17]4[cH:18][n:19][cH:20][s:21]4)[cH:16]3)[n:7][cH:8][cH:9]2)[CH2:2][CH2:3]1.[Li+:23].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[CH:1]1([c:4]2[n:5][c:6]([NH:10][c:11]3[cH:12][c:13]([CH3:22])[cH:14][c:15](-[c:17]4[cH:18][n:19][c:20]([C:31]5([NH:35][S:36](=[O:37])[C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:32][CH2:33][CH2:34]5)[s:21]4)[cH:16]3)[n:7][cH:8][cH:9]2)[CH2:2][CH2:3]1
