Chloride → Methyl {4-[4-(2-bromo-2-methylpropanoyl)phenyl]bicyclo[2.2.2]oct-1-yl}acetate

HRID 1118031

Reaction equation

HRID 1118031 reaction equation
[Al+3:22].[Br:25][C:26]([C:27](=[O:28])[Br:29])([CH3:30])[CH3:31].[Cl-:21].[Cl-:23].[Cl-:24].[Cl:32][CH2:33][Cl:34].[OH2:1].[c:2]1([C:8]23[CH2:9][CH2:10][C:11]([CH2:16][C:17](=[O:18])[O:19][CH3:20])([CH2:12][CH2:13]2)[CH2:14][CH2:15]3)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:8]23[CH2:9][CH2:10][C:11]([CH2:16][C:17](=[O:18])[O:19][CH3:20])([CH2:12][CH2:13]2)[CH2:14][CH2:15]3)[cH:3][cH:4][c:5]([C:27]([C:26]([Br:25])([CH3:30])[CH3:31])=[O:28])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 312Chloride3×HCID 962WaterHCID 6344DichloromethaneHCID 886852-Bromo-2-methylpropionyl bromideHCID 104727Aluminum CationHCID 25016427Methyl (4-phenylbicyclo[2.2.2]oct-1-yl)acetate

Product 1

HCID 25258107Methyl {4-[4-(2-bromo-2-methylpropanoyl)phenyl]bicyclo[2.2.2]oct-1-yl}acetate

Sources & evidence

ORD record
ord-274d80e061ae4819b8077077bc79e7ed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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