Triethylamine → 3-(3,4-Difluoro-phenylethynyl)-phenylamine

HRID 1125762

Reaction equation

HRID 1125762 reaction equation
[CH3:78][CH2:79][N:80]([CH2:81][CH3:82])[CH2:83][CH3:84].[F:1][c:2]1[cH:3][c:4]([Br:9])[cH:5][cH:6][c:7]1[F:8].[I-:38].[NH2:10][c:11]1[cH:12][c:13]([C:17]#[CH:18])[cH:14][cH:15][cH:16]1.[Pd:39].[c:19]1([P:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:33][cH:34][cH:35][cH:36][cH:37]1.[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1.[c:59]1([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[cH:73][cH:74][cH:75][cH:76][cH:77]1>>[F:1][c:2]1[cH:3][c:4]([C:18]#[C:17][c:13]2[cH:12][c:11]([NH2:10])[cH:16][cH:15][cH:14]2)[cH:5][cH:6][c:7]1[F:8]

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 11776Triphenylphosphine3×HCID 23938PalladiumHCID 30165Iodide IonHCID 676754-Bromo-1,2-difluorobenzeneHCID 104682Benzenamine, 3-ethynyl-

Product 1

HCID 198210783-(3,4-Difluoro-phenylethynyl)-phenylamine

Sources & evidence

ORD record
ord-8d6e01107f4244f68950d60acff03a6b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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