Sodium ion → N-(Cyclopropylmethyl)-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide

HRID 1130134

Reaction equation

[Br:28][CH2:29][CH:30]1[CH2:31][CH2:32]1.[CH3:1][c:2]1[n:3][n:4][c:5]2[n:6]1[n:7][c:8](-[c:11]1[cH:12][c:13]([NH:17][C:18]([CH3:19])=[O:20])[cH:14][cH:15][cH:16]1)[cH:9][cH:10]2.[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[H-:21].[Na+:22].[OH2:33]>>[CH3:1][c:2]1[n:3][n:4][c:5]2[n:6]1[n:7][c:8](-[c:11]1[cH:12][c:13]([N:17]([C:18]([CH3:19])=[O:20])[CH2:29][CH:30]3[CH2:31][CH2:32]3)[cH:14][cH:15][cH:16]1)[cH:9][cH:10]2

Participants

Reactant 6

HCID 923Sodium ion

HCID 962Water

HCID 6228Dimethylformamide

HCID 81503Bromomethylcyclopropane

HCID 166653Hydride

HCID 7532415N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide

Product 1

HCID 15595652N-(Cyclopropylmethyl)-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide

Sources & evidence

ORD record: ord-8e5ed00ced0a4c65b35003c34939ca20
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Linked notes

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