Diethyl Ether → (1-Benzylpiperidin-4-yl)methanol

HRID 113146

Reaction equation

HRID 113146 reaction equation
[Al+3:20].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:12][CH2:13]1.[CH3:25][CH2:26][O:27][CH2:28][CH3:29].[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][OH:15])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 28486Lithium ionHCID 90423Ethyl 1-benzylpiperidine-4-carboxylateHCID 104727Aluminum CationHCID 166653Hydride4×

Product 1

HCID 736802(1-Benzylpiperidin-4-yl)methanol

Sources & evidence

ORD record
ord-f69f2d8053ec4482a3d498d5cc1750ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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