Hydroxide → tert-butyl N-[1-[5-bromo-3-(propanoylamino)-1H-pyrrolo[2,3-b]pyridin-4-yl]piperidin-3-yl]carbamate
Reaction equation
[C:1]([CH2:2][CH3:3])(=[O:4])[Cl:5].[CH3:33][N:34]1[CH2:35][CH2:36][CH2:37][C:38]1=[O:39].[Cl:40][CH2:41][Cl:42].[Li+:32].[NH2:6][c:7]1[cH:8][nH:9][c:10]2[n:11][cH:12][c:13]([Br:30])[c:14]([N:16]3[CH2:17][CH:18]([NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:19][CH2:20][CH2:21]3)[c:15]12.[OH-:31].[OH2:43].[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1>>[C:1]([CH2:2][CH3:3])(=[O:4])[NH:6][c:7]1[cH:8][nH:9][c:10]2[n:11][cH:12][c:13]([Br:30])[c:14]([N:16]3[CH2:17][CH:18]([NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:19][CH2:20][CH2:21]3)[c:15]12
