Hydrochloric Acid → 2-[5-chloro-6-(trifluoromethyl)pyrimidin-4-yl]oxy-N-(1-cyanocyclopentyl)propanamide

HRID 1143124

Reaction equation

HRID 1143124 reaction equation
[CH2:2]([N:3]=[C:4]=[N:5][CH2:6][CH2:7][CH2:8][N:9]([CH3:10])[CH3:11])[CH3:12].[CH:39]([Cl:40])([Cl:41])[Cl:42].[Cl:13][c:14]1[c:15]([O:24][CH:25]([C:26](=[O:27])[OH:28])[CH3:29])[n:16][cH:17][n:18][c:19]1[C:20]([F:21])([F:22])[F:23].[ClH:1].[NH2:30][C:31]1([C:36]#[N:37])[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:38]>>[Cl:13][c:14]1[c:15]([O:24][CH:25]([C:26](=[O:28])[NH:30][C:31]2([C:36]#[N:37])[CH2:32][CH2:33][CH2:34][CH2:35]2)[CH3:29])[n:16][cH:17][n:18][c:19]1[C:20]([F:21])([F:22])[F:23]

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 962WaterHCID 6212ChloroformHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 21068971-AminocyclopentanecarbonitrileHCID 187002832-[5-Chloro-6-(trifluoromethyl)pyrimidin-4-yl]oxypropanoic acid

Product 1

HCID 187002842-[5-chloro-6-(trifluoromethyl)pyrimidin-4-yl]oxy-N-(1-cyanocyclopentyl)propanamide

Sources & evidence

ORD record
ord-64ac256ff85849f99391471f023d565b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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