Tetrahydrofuran → [3-(2-Methyl-1,3-dioxolan-2-yl)tricyclo[3.3.1.03,7]non-1-yl]methanol

Reaction equation

[Al+3:21].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:1][C:2]1([C:7]23[CH2:8][C:9]4([C:16](=[O:17])[O:18][CH3:19])[CH2:10][CH:11]2[CH2:12][CH:13]([CH2:14]3)[CH2:15]4)[O:3][CH2:4][CH2:5][O:6]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22]>>[CH3:1][C:2]1([C:7]23[CH2:8][C:9]4([CH2:16][OH:17])[CH2:10][CH:11]2[CH2:12][CH:13]([CH2:14]3)[CH2:15]4)[O:3][CH2:4][CH2:5][O:6]1

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 67017820Methyl 3-(2-methyl-1,3-dioxolan-2-yl)tricyclo[3.3.1.03,7]nonane-1-carboxylate

Product 1

HCID 59374962[3-(2-Methyl-1,3-dioxolan-2-yl)tricyclo[3.3.1.03,7]non-1-yl]methanol

Sources & evidence

ORD record: ord-303bef2e48d6413a955cf9a85c9406c2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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