Iodide Ion → 2-Hydroxy-2-(4-isobutylphenyl)acetonitrile

Reaction equation

[CH2:1]([CH:2]([CH3:3])[CH3:4])[c:5]1[cH:6][cH:7][c:8]([CH:9]=[O:10])[cH:11][cH:12]1.[CH3:13][Si:14]([CH3:15])([CH3:16])[C:17]#[N:18].[I-:19].[I-:21].[Zn+2:20]>>[CH2:1]([CH:2]([CH3:3])[CH3:4])[c:5]1[cH:6][cH:7][c:8]([CH:9]([OH:10])[C:17]#[N:18])[cH:11][cH:12]1

Participants

Reactant 4

HCID 30165Iodide Ion2×

HCID 32051Zinc(2+)

HCID 82115Trimethylsilyl cyanide

HCID 577537Benzaldehyde, 4-(2-methylpropyl)-

Product 1

HCID 190247872-Hydroxy-2-(4-isobutylphenyl)acetonitrile

Sources & evidence

ORD record: ord-40c6c85fcf8646f59e866cbbc714839a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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