Diethyl Ether → 3-(1-Benzylpiperidin-4-yl)-7-fluoro-3,4-dihydroquinazolin-2(1H)-one
Reaction equation
[C:1](=[O:2])([n:3]1[cH:4][cH:5][n:6][cH:7]1)[n:8]1[cH:9][cH:10][n:11][cH:12]1.[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[NH2:13][c:14]1[c:15]([CH2:16][NH:17][CH:18]2[CH2:19][CH2:20][N:21]([CH2:24][c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:22][CH2:23]2)[cH:31][cH:32][c:33]([F:35])[cH:34]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[C:1]1(=[O:2])[NH:13][c:14]2[c:15]([cH:31][cH:32][c:33]([F:35])[cH:34]2)[CH2:16][N:17]1[CH:18]1[CH2:19][CH2:20][N:21]([CH2:24][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[CH2:22][CH2:23]1Participants
5
Sources & evidence
- ORD record
- ord-85d6de16b1454cbc833446c2196cdd90