Ammonium → 5-Bromo-2-(4-cyclohexyl-3-trifluoromethyl-benzyloxy)-pyridine

HRID 116097

Reaction equation

HRID 116097 reaction equation
[CH:1]1([c:7]2[c:8]([C:15]([F:16])([F:17])[F:18])[cH:9][c:10]([CH2:13][OH:14])[cH:11][cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[Cl-:29].[Cl:21][c:22]1[n:23][cH:24][c:25]([Br:28])[cH:26][cH:27]1.[H-:19].[NH4+:30].[Na+:20].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[CH:1]1([c:7]2[c:8]([C:15]([F:16])([F:17])[F:18])[cH:9][c:10]([CH2:13][O:14][c:22]3[n:23][cH:24][c:25]([Br:28])[cH:26][cH:27]3)[cH:11][cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 27344145-Bromo-2-chloropyridineHCID 22057748[4-Cyclohexyl-3-(trifluoromethyl)phenyl]methanol

Product 1

HCID 688136965-Bromo-2-(4-cyclohexyl-3-trifluoromethyl-benzyloxy)-pyridine

Sources & evidence

ORD record
ord-cfe4e63ad5e649cf921ddc9450937639
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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