Urea → 1H-Imidazo[4,5-f]quinolin-2(3H)-one
Reaction equation
[NH2:1][C:2]1[C:11]([N+:12]([O-])=O)=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2.N[C:16](N)=[O:17]>COCCOCCOC>[NH:1]1[C:2]2[C:3]3[CH:4]=[CH:5][CH:6]=[N:7][C:8]=3[CH:9]=[CH:10][C:11]=2[NH:12][C:16]1=[O:17]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Quinolino[5,6-d]imidazolinone (2f) was prepared from 5-amino-6-nitroquinoline by hydrogenation and subsequent treatment with urea in diglyme. Overall yield: 91%.
Sources & evidence
- ORD record
- ord-68a1d59c06b7490ea4ff7c9f4364663f
- Source dataset
- uspto-grants-2003_09
- Patent number
- US06624186B2
Reaction notes
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