Tetrahydrofuran → 1-Benzyl-3-methylpiperidin-4-ol

HRID 117129

Reaction equation

HRID 117129 reaction equation
[Al+3:2].[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[N:14]1[CH2:15][CH:16]([CH3:21])[C:17](=[O:20])[CH2:18][CH2:19]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1>>[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[N:14]1[CH2:15][CH:16]([CH3:21])[CH:17]([OH:20])[CH2:18][CH2:19]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 5609651-Benzyl-3-methyl-4-piperidone

Product 1

HCID 136114921-Benzyl-3-methylpiperidin-4-ol

Sources & evidence

ORD record
ord-0cb80dba1bdc4f4e83265cefed19acbb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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