Water → 1-Benzyl-4-(pyridin-3-YL)piperidin-4-OL

HRID 118573

Reaction equation

HRID 118573 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[N:20]1[CH2:21][CH2:22][C:23](=[O:26])[CH2:24][CH2:25]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:28][O:29][C:30]([CH3:31])([CH3:32])[CH3:33].[OH2:27]>>[c:2]1([C:23]2([OH:26])[CH2:22][CH2:21][N:20]([CH2:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:25][CH2:24]2)[cH:3][n:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 122863-BromopyridineHCID 15413tert-Butyl methyl etherHCID 192201-Benzyl-4-piperidoneHCID 178418339Butyllithium

Product 1

HCID 10940791-Benzyl-4-(pyridin-3-YL)piperidin-4-OL

Sources & evidence

ORD record
ord-b70745f4c8594d658a5e466c3a7886be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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