Dimethylformamide → 5-Amino-N-(2-{[ethyl(phenylmethyl)amino]methyl}-3,3,3-trifluoro-2-hydroxypropyl)-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide
Reaction equation
[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[NH2:10][c:11]1[c:12]([C:23](=[O:24])[OH:25])[cH:13][n:14][n:15]1-[c:16]1[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]1.[NH2:26][CH2:27][C:28]([C:29]([F:30])([F:31])[F:32])([OH:33])[CH2:34][N:35]([CH2:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)[CH2:43][CH3:44]>>[NH2:10][c:11]1[c:12]([C:23](=[O:25])[NH:26][CH2:27][C:28]([C:29]([F:30])([F:31])[F:32])([OH:33])[CH2:34][N:35]([CH2:36][c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[CH2:43][CH3:44])[cH:13][n:14][n:15]1-[c:16]1[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]1Participants
5
