Hydrochloric Acid → N-Cyclopropyl-4-fluoro-3-[2-(pyridin-2-ylamino)-thiazol-5-ylmethoxy]-benzamide

HRID 1212845

Reaction equation

HRID 1212845 reaction equation
[Cl:16][CH2:17][c:18]1[cH:19][n:20][c:21]([NH:23][c:24]2[n:25][cH:26][cH:27][cH:28][cH:29]2)[s:22]1.[ClH:15].[K+:35].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH:8]2[CH2:9][CH2:10]2)[cH:11][cH:12][c:13]1[F:14].[S:30](=[O:31])(=[O:32])([OH:33])[O-:34]>>[O:1]([c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH:8]2[CH2:9][CH2:10]2)[cH:11][cH:12][c:13]1[F:14])[CH2:17][c:18]1[cH:19][n:20][c:21]([NH:23][c:24]2[n:25][cH:26][cH:27][cH:28][cH:29]2)[s:22]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 6228DimethylformamideHCID 61778Sulfate, hydrogenHCID 220191035-(chloromethyl)-N-pyridin-2-yl-1,3-thiazol-2-amineHCID 220191063-hydroxy-4-fluoro-N-cyclopropylbenzamide

Product 1

HCID 22019135N-Cyclopropyl-4-fluoro-3-[2-(pyridin-2-ylamino)-thiazol-5-ylmethoxy]-benzamide

Sources & evidence

ORD record
ord-fddd6521038445b98729b0629d106245
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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