Water → 6-(4-amino-3-chlorophenyl)-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one

Reaction equation

[CH3:24][N:25]([CH3:26])[CH:27]=[O:28].[Cl:16][N:17]1[C:18](=[O:19])[CH2:20][CH2:21][C:22]1=[O:23].[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:13][NH:12][C:11](=[O:14])[NH:10][CH:9]2[CH3:15])[cH:6][cH:7]1.[OH2:29]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:13][NH:12][C:11](=[O:14])[NH:10][CH:9]2[CH3:15])[cH:6][c:7]1[Cl:16]

Participants

Reactant 4

HCID 962Water

HCID 6228Dimethylformamide

HCID 31398Chlorosuccinimide

HCID 133860336-(4-aminophenyl)-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one

Product 1

HCID 133860536-(4-amino-3-chlorophenyl)-5-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one

Sources & evidence

ORD record: ord-bae80909f8de4748ac5bd445b526849f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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