Sodium Ion → (2-(1,1-Dimethylethyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol

Reaction equation

[Al+3:30].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[c:6](-[c:15]2[c:16]([F:23])[cH:17][cH:18][c:19]([O:21][CH3:22])[cH:20]2)[cH:7][cH:8][c:9]([C:11](=[O:12])[O:13][CH3:14])[cH:10]1.[H-:29].[H-:32].[H-:33].[H-:34].[Li+:31].[Na+:36].[OH-:35]>>[CH3:1][C:2]([CH3:3])([CH3:4])[c:5]1[c:6](-[c:15]2[c:16]([F:23])[cH:17][cH:18][c:19]([O:21][CH3:22])[cH:20]2)[cH:7][cH:8][c:9]([CH2:11][OH:12])[cH:10]1

Participants

Reactant 7

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 57705886Methyl 2-(1,1-dimethylethyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-carboxylate

Product 1

Sources & evidence

ORD record: ord-33802bf75bbb498fb83ad8e6aad238ac
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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