Isopropanol → 2-Chloro-4-isopropoxypyrimidine

Reaction equation

[C:9](=[O:10])([O-:11])[O-:12].[CH3:15][CH:16]([CH3:17])[OH:18].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([Cl:8])[n:7]1.[Cs+:13].[Cs+:14]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:18][CH:16]([CH3:15])[CH3:17])[n:7]1

Participants

Reactant 4

HCID 3776Isopropanol

HCID 19660Carbonate Ion

HCID 775312,4-Dichloropyrimidine

HCID 104967Cesium cation2×

Product 1

HCID 623383092-Chloro-4-isopropoxypyrimidine

Sources & evidence

ORD record: ord-c82e436414e743ddadf88f82a17a0423
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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