Hydrogen Bromide → HCID 13561737, compound
Reaction equation
[CH3:1][C:2]([CH3:9])([CH2:6][CH:7]=[CH2:8])[C:3](=[O:5])[CH3:4].[BrH:10]>C(Cl)(Cl)Cl.[Fe]>[Br:10][CH:7]([CH3:8])[CH2:6][C:2]([CH3:9])([CH3:1])[C:3](=[O:5])[CH3:4]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
18.9 g (0.15 mole) of 3,3-dimethyl-5-hexen-2-one and 1.6 g (0.0054 mole) of iron-III bromide are dissolved in 150 ml of chloroform. 0.16 mole of hydrogen bromide gas are passed in at 0° C. in the course of 90 minutes. The mixture is subsequently stirred at room temperature for 2 hours and the organic phase is separated off, washed with water, dried over sodium sulphate and concentrated in vacuo. 27 g (87% of theory) of 5-bromo-3,3-dimethyl-2-hexanone of refractive index nD20 =1.4639 are obtained.
Workup
- customare passed in at 0° C. in the course of 90 minutes
- customthe organic phase is separated off
- washwashed with water
- dry with materialdried over sodium sulphate
- concentrationconcentrated in vacuo
Sources & evidence
- ORD record
- ord-24bc4bc54f8e4d8ab29ec80028af93e7
- Source dataset
- uspto-grants-1988_05
- Patent number
- US04748249
Reaction notes
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