Tetrahydrofuran → 2-(2-Chloro-3-fluoropyridin-4-yl)propan-2-ol

HRID 125764

Reaction equation

HRID 125764 reaction equation
[CH2:17]1[CH2:20][CH2:19][CH2:18][O:21]1.[CH:1]([CH3:2])([CH3:3])[N-:4][CH:5]([CH3:6])[CH3:7].[Cl:9][c:10]1[n:11][cH:12][cH:13][cH:14][c:15]1[F:16].[Li+:8]>>[C:1]([CH3:2])([CH3:3])([c:14]1[cH:13][cH:12][n:11][c:10]([Cl:9])[c:15]1[F:16])[OH:21]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 27827912-Chloro-3-fluoropyridineHCID 5062348Diisopropylamide

Product 1

HCID 179648322-(2-Chloro-3-fluoropyridin-4-yl)propan-2-ol

Sources & evidence

ORD record
ord-fef509482aa3443eaabf64cd033d4861
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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