N-Methylbenzylamine → N-methoxyethyl-N-methylbenzylamine
Reaction equation
[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:10][O:11][CH2:12][CH2:13]Br>C(O)C>[CH3:10][O:11][CH2:12][CH2:13][N:2]([CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:1]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The synthesis of BnMO was carried out in a manner similar to that of BnEO (process 2) using N-methylbenzylamine (15 mL, 0.116 mol), bromoethyl methyl ether (12 mL, 0.116×1.1 mmol), and ethanol (200 mL) as a solvent. BnMO (12.09 g, 67.46 mmol, yield 58%) was obtained as a pale yellow clear liquid.
Workup
- customThe synthesis of BnMO
- customBnMO (12.09 g, 67.46 mmol, yield 58%) was obtained as a pale yellow clear liquid
Sources & evidence
- ORD record
- ord-b3d702dd81b64101bc4909d8858fe53e
- Source dataset
- uspto-grants-2013_06
- Patent number
- US08466287B2
Reaction notes
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